SirnBIO-TECH Talk to Us
Search by product name, Latin name or CAS number.
Precision Phytochemical Actives
Standardized Herbal Extracts & Specialty Botanicals
Engineered for international contract manufacturers, functional beverage formulators, and dietary supplement brands requiring batch-to-batch chromatographic consistency and exhaustive regulatory documentation.
Glucosinolates
Wholesale Factory Supply Watercress Extract Watercress Powder Price for Sale
Botanical:Nasturtium officinale
Extraction Ratio:10:1 / 20:1 / Pure
Assay Method:TLC / UV-Vis
Lead Application:Detox & Metabolic Blends
Annonaceous Acetogenins
Hot Selling High Quality Natural Guanabana/Graviola/Soursop Leaf Extract
Botanical:Annona muricata L.
Specification:10:1 / Flavonoids ≥5%
Mesh Profile:100% Pass 80 Mesh
Lead Application:Cellular Health Formulations
Polyphenols
Manufacturer Supply High Quality Graviola Leaf Extract Soursop Leaves Powder
Botanical:Annona muricata Folium
Solvent Base:Hydroalcoholic / Water
Quality Control:Non-Irradiated / ETO-Free
Lead Application:Immune Support Capsules
Lipid Carotenoid
Factory Supply Best Price Astaxanthin Oil for Supplement Plant Extract
Source:Haematococcus pluvialis
Potency:5% / 10% Oleoresin Oil
Assay Method:HPLC Chromatography
Lead Application:Antioxidant Softgels
Aromatic Glycosides
High Quality Plant Extract Osmanthus Flower Extract
Botanical:Osmanthus fragrans
Aroma Profile:Natural Volatile Floral
Solubility:100% Water Dispersible
Lead Application:RTD Functional Beverages
Hericenones & Erinacines
Best Price Bulk Food Grade Lions Mane Dual Extract Powder Drum Packaging
Botanical:Hericium erinaceus
Extraction:Water & Alcohol Dual
Active Markers:Polysaccharides ≥30% (UV)
Lead Application:Nootropic & Coffee Blends
Anthocyanins ≥15%
Aronia Berry Powder, Aronia Extract, Water-soluble Concentrate
Botanical:Aronia melanocarpa
Active Markers:Anthocyanins & PACs
Solubility:Instant Clear in Water
Lead Application:Cardiovascular Clean-Label
Chlorogenic Acid
Factory Supply Best Quality Natural Ionicera Edulis Extract
Botanical:Lonicera caerulea L.
Bioactive Base:Cyanidin-3-Glucoside (C3G)
Purity Grade:HPLC Quantified Active
Lead Application:Ocular & Metabolic Health
Procurement Intelligence & Market Dynamics
The Strategic Shift in Global Botanical Extract Sourcing
Analyzing regulatory hurdles, supply security, HPLC fingerprinting adoption, and the phase-out of traditional non-standardized extraction methodologies across tier-1 nutraceutical markets.
>68%
Global Extract Market Share from China
HPLC/GC
Mandatory Chromatographic Verification
<0.01 ppm
Target Residual Solvent Thresholds
100%
Batch Botanical DNA & Fingerprint ID
1. Paradigm Shift: From Crude Ratios to Fingerprinted Actives
The international dietary supplement landscape has officially moved beyond deceptive generic ratios like "10:1" or "20:1" without verifiable marker quantification. Regulatory bodies such as the US FDA (21 CFR Part 111) and the European Food Safety Authority (EFSA) demand validated chromatographic data.
Modern procurement heads are prioritizing Multi-Marker HPLC & UHPLC Fingerprinting. This guarantees that key target molecules—such as hericenones in Hericium erinaceus, anthocyanins in Aronia berries, and icariin in Epimedium—remain chemically identical between batches, eliminating the risk of adulteration with low-cost carrier maltodextrin.
2. Stringent Pesticide, Heavy Metal & PAH4 Standards
Cross-border compliance failures are predominantly triggered by unmonitored agrochemical residues and polycyclic aromatic hydrocarbons (PAHs). With the EU amending Regulation (EC) No 396/2005 and tightening chlorpyrifos limits to the limit of quantification (0.01 mg/kg), sourcing from unverified brokers poses catastrophic recall risks.
Export-oriented extraction facilities in China must deploy ICP-MS (Inductively Coupled Plasma Mass Spectrometry) and GC-MS/MS platforms to enforce USP <561> compliance, ensuring lead (Pb), cadmium (Cd), arsenic (As), and mercury (Hg) remain well below pharmacopeial thresholds prior to shipping.
3. Solvent Safety & Clean-Label Extraction Engineering
The global clean-label revolution has rendered Class 1 and Class 2 solvents (such as hexane, chloroform, and methanol) obsolete in premium nutraceutical processing. Today's supply chains demand clean extraction media, centering around water-only extraction, food-grade bio-fermented ethanol, or supercritical CO2 fluid processing.
Furthermore, for high-end functional foods and instant powders, spray-drying and freeze-drying operations must achieve instant water reconstitution without clumping, utilizing vacuum low-temperature evaporation to prevent the thermal degradation of delicate anthocyanins and polyphenolic ring structures.
Academic Rigor · Industrial Scale
Xi'an Botanical Epicenter: Advanced Extraction Infrastructure
Located at the geographic origin of the ancient Silk Road in Xi'an, Shaanxi Province, our manufacturing operations benefit from direct geographical proximity to the Qinling Mountains—the biological treasury containing over 3,000 documented traditional medicinal flora species.
Xi'an Sirn Bio-Tech Co., Ltd. bridges raw agricultural abundance with cutting-edge separation engineering. Operating two modern manufacturing facilities equipped with 4 automated continuous extraction lines, 2 dedicated pilot lines, and a full GMP standard cleanroom workshop, we scale formulas from exploratory 1 kg lab lots to multi-ton industrial batches without modifying extraction kinetics or thermal parameters.
- Chromatographic Testing Suite: In-house HPLC, Gas Chromatography (GC), and UV-Vis spectrophotometers ensuring every single batch matches its COA.
- Human Capital Excellence: Our technical operations are led by 18 mid-to-senior bio-engineers and 5 licensed Traditional Chinese Medicine (TCM) pharmacists.
- Ultra-Low Batch Threshold: Flexible supply chain designed for international R&D trials: 1 kg MOQ for standardized powders, accelerating formulation lifecycles.
- Rapid Technical SLA: 99% buyer message response rate with detailed technical specification packages delivered within 2 business hours.
Academic Joint Research Laboratories
To resolve deep challenges in stereoisomeric separation, bio-active degradation, and peptide stability, our R&D division co-operates joint research and development laboratories with leading Chinese academic institutions:
Xi'an Jiaotong University
Northwest University
Xi'an Univ. of Science & Technology
These collaborative platforms grant our overseas formulation clients direct access to high-resolution Nuclear Magnetic Resonance (NMR), LC-MS/MS molecular weight confirmation, and targeted in-vitro antioxidant assays.
Precision Manufacturing Traceability
Standardized 8-Stage Extraction & Quality Control Flow
Every kilogram of botanical extract manufactured in our GMP workshop follows an uninterrupted chain of custody, ensuring total audit readiness for international import clearance.
Stage 01
Raw Herb Authentication
Botanical taxonomy, wildcraft/cultivation origin verification, and visual macro/microscopic identification by licensed TCM pharmacists.
Stage 02
Quarantine & Analytical Screening
Initial inspection of moisture levels, ash content, organoleptic metrics, and preliminary screening for heavy metals and pesticides.
Stage 03
Dynamic Targeted Extraction
Multi-stage countercurrent extraction utilizing thermodynamic temperature regulation, ultrasonic assistance, or water/ethanol solvent matrices.
Stage 04
Centrifugal Filtration & Evaporation
High-speed disc centrifugation and falling-film low-temperature vacuum evaporation to concentrate phytocompounds without thermal denaturation.
Stage 05
Macroporous Resin Purification
Chromatographic resin column adsorption and desorption to eliminate impurities and systematically isolate target bioactive fractions.
Stage 06
Aseptic Drying & Granulation
High-efficiency spray drying for extract powders or low-temperature freeze drying (lyophilization) for thermolabile compounds and whole berries.
Stage 07
Batch Analytical Release (COA)
Final HPLC/UV potency assay, heavy metals via ICP-MS, residual solvent GC verification, and AOAC total microbial pathogen screening.
Stage 08
Sealing, Inert Gas Flush & Dispatch
Packaging in double pharmaceutical-grade polyethylene liner bags encased within multi-ply aluminum foil or fiberboard drums with tamper-proof seal.
Procurement Intelligence
Frequently Asked Questions by Global Sourcing Directors
Concrete technical, logistical, and compliance responses to the questions most frequently evaluated by quality assurance directors and supply chain executives.
How do you guarantee botanical identity and prevent economically motivated adulteration (EMA)?
We employ orthogonal testing methodologies combining High-Performance Thin-Layer Chromatography (HPTLC) against authenticated botanical reference standards and HPLC characteristic fingerprinting. When requested for high-risk botanicals, we provide DNA barcoding (ITS2 or rbcL genomic sequencing) conducted in partnership with our academic joint labs to unequivocally verify the exact species before raw herb processing begins.
What is your protocol for pesticide residues and ethylene oxide (ETO) treatment?
Our extracts are 100% ethylene oxide (ETO) free and non-irradiated. Sterilization is executed via physical methods including high-temperature short-time (HTST) steam sterilization or clean gamma irradiation only upon explicit client request. Every export batch is tested against USP <561> multi-residue pesticide screens covering over 70 target compounds, ensuring zero regulatory detainments by the US FDA or EU borders.
What documentation accompanies every commercial shipment?
Every shipment arrives with a complete batch documentation package: Official Certificate of Analysis (COA) specifying test methodologies, Safety Data Sheet (SDS / MSDS) compliant with GHS, Detailed Manufacturing Process Flow Chart, Non-GMO Statement, Allergen Declaration, Bovine/TSE/BSE Free Statement, and Certificate of Origin (COO) to facilitate favorable tariff classification.
Can you provide custom mesh sizes, solubility profiles, and carrier-free formulations?
Yes. Through our 2 dedicated pilot lines, we offer customized milling from standard 80 mesh up to ultra-fine 300 mesh micronized powders. Furthermore, for functional RTD beverages and sachet formulations, we engineer agglomerated instant water-soluble granules. We can manufacture 100% carrier-free powders or formulate with specified organic maltodextrin/acacia gum based on your target formulation constraints.
What are your standard minimum order quantities (MOQ) and production lead times?
For standardized catalogue powders and extracts, our MOQ starts at just 1 kg packed in heat-sealed aluminum foil pouches, enabling formulation testing and pilot clinicals without capital overextension. Commercial drum quantities (25 kg fiberboard drums) for inventory items dispatch within 48 to 72 hours. Custom contract manufacturing runs typically carry a 10 to 14-day production lead time.
Do you support pre-shipment third-party verification through laboratories like Eurofins or SGS?
Absolutely. We frequently collaborate with independent ISO 17025 accredited laboratories including Eurofins, SGS, and Pony Testing. Clients can request pre-shipment sampling and testing at an independent facility of their choosing. Commercial goods remain sequestered under quarantine until third-party results correlate directly with our in-house Certificate of Analysis.