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Precision Formulations & Botanical Precursors
Featured Standardized Extracts for Immediate Dispatch
Explore 8 core standardized functional botanicals engineered at Xi'an Sirn Bio-Tech's cGMP workshops. Complete with HPLC/UV batch assay validation, ultra-low pesticide screens, and custom mesh granulation.
Adaptogen Grade
High Quality Dry Cordyceps Extract Powder for Capsule Supplement
- Active Marker: Polysaccharides ≥40%
- Assay Method: UV-Vis / HPLC
- Key Use: ATP Synthesis & Immunity
Anthocyanin Pure
High Quality Water Soluble Cherry Extract Powder Grade Food Fruit Extract
- Active Marker: Anthocyanins ≥10%
- Solubility: 100% Cold Water Soluble
- Key Use: Antioxidant / Uric Acid
Pharmacopeial
Hot Sale Factory Ginseng Extract Red Ginseng Ginsenosides
- Active Marker: Ginsenosides 10%–80%
- Assay Method: HPLC (Rg1, Re, Rb1)
- Key Use: Metabolic / Cognitive Tonic
Phytomedicine
Hot Selling High Quality Natural Guanabana/Graviola/Soursop Leaf Extract
- Extraction Ratio: 10:1 / 20:1 TLC Pure
- Phytochemicals: Flavonoids & Acetogenins
- Key Use: Cellular Cytoprotection
Cosmeceutical
High Quality Plant Extract Osmanthus Flower Extract
- Active Marker: Total Flavonoids ≥15%
- Mesh Size: 80–100 Mesh Fine
- Key Use: Anti-Glycation & Aroma
Polyphenol Pure
High Purity 100% Water Soluble Instant Black Tea Powder High Quantity High Tea
- Active Marker: Theaflavins & Polyphenols
- Solubility: Instant Clarified Solution
- Key Use: Cardiovascular RTD Drinks
Functional Carrier
Best selling products natural taro milk tea coconut powder
- Processing: Spray-Dried Micro-Emulsion
- Characteristics: Lipid-Matrix Stabilized
- Key Use: Nutritional Meal Base
Superfruit Active
Hot Sale High Quality Prickly Pear Extract Powder Rosa Roxburghii Fruit Powder
- Active Markers: Vitamin C + Flavonoids
- Source: Rosa Roxburghii Tratt
- Key Use: SOD Elevation & Dermal Health
2
Dedicated GMP Extraction Works
6
Continuous & Pilot Scale Lines
18
Mid/Senior Chemical Technicians
3
University Joint Research Centers
≤2h
Technical Response SLA for Odesa
Industrial Phytochemistry Whitepaper
Engineering Bioflavonoids: Molecular Fingerprinting & Separation
Bioflavonoids represent a sophisticated cluster of secondary plant polyphenols characterized by a phenylbenzopyran core architecture (C6-C3-C6 backbone). In commercial bio-processing, procuring high-efficacy flavonoid fractions is frequently hindered by batch variance, native glycosylation profiles, solvent degradation, and co-eluting non-target tannins. For industrial enterprises across Odesa and the Black Sea region, sourcing directly from audited Chinese botanical extraction centers guarantees high bioavailability, exact aglycone-to-glycoside balances, and pharmacopeial purity verified through high-performance liquid chromatography (HPLC).
Subclass Standardization
We isolate distinct chemical families: Flavonols (Quercetin, Kaempferol, Myricetin), Flavones (Luteolin, Apigenin), Flavanones (Hesperidin, Naringin), and Flavan-3-ols (Theaflavins, EGCG). Each subclass demands targeted pH-buffered hydro-ethanolic conditions to prevent degradation of phenolic hydroxyls.
Macroporous Resin Adsorption
Our Shaanxi facilities operate pressurized continuous resin columns utilizing non-polar to mid-polar polymeric adsorbents (AB-8, D101, and HPD-series). This process strips free monosaccharides, lipids, and heavy salts, concentrating targeted bioflavonoid fractions from raw slurries to ≥98% purity.
Low-Temperature Vacuum Drying
Bioflavonoids undergo thermolabile degradation at continuous exposures above 60°C. We implement continuous thin-film rotary evaporation and low-temperature vacuum belt drying (or flash spray drying with inert nitrogen protection), preserving native antioxidant ring configurations.
| Target Flavonoid Fraction | Botanical Source Matrix | Industry Standard Assay | Common Adulteration Risk | Sirn Bio-Tech QC Standard |
|---|---|---|---|---|
| Quercetin / Rutin NF/EP | Sophora japonica L. (Buds) | HPLC (Isocratic C18) | Synthetic Rutin spikes, unreacted sulfates | ≥98.0% Dry Basis; Residual Ethanol <500ppm |
| Epimedium Icariin | Epimedium brevicornu Maxim. | HPLC (Gradient Acetonitrile-H2O) | Crude ratio powders cut with maltodextrin | 10% to 98% Icariin, Total Flavonoids ≥50% |
| Citrus Bioflavonoid Complex | Citrus aurantium L. | UV-Vis (Total) / HPLC (Hesperidin) | Naringin spiked as Hesperidin; chalky fillers | Total Flavonoids 50%–70%, Hesperidin quantified |
| Theaflavins & Catechins | Camellia sinensis | HPLC (TF1, TF2a, TF2b, TF3) | Low-grade tea dust waste with heavy lead loads | Total Theaflavins ≥30%, Instant cold solubility |
*Analytical cross-validation performed via Agilent 1260 Infinity II HPLC coupled with Diode Array Detectors (DAD) and Single Quadrupole LC/MS. Every export shipment to Odesa includes an individual lot Certificate of Analysis (COA).
Regional Manufacturing Synergy
Localized Industrial Applications Across Odesa & Southern Ukraine
Odesa functions as the undisputed maritime industrial gateway and logistics heartland for Ukraine's healthcare, chemical, and agro-processing industries. The unique commercial climate of Odesa Oblast—characterized by strong historical pharmaceutical institutions, active phytotherapy research, leading viticulture and enological centers, and expanding FMCG manufacturing—creates distinct requirements for high-spec botanical raw materials.
1. Phlebological & Venotonic Drug Formulation
Odesa's pharmaceutical laboratories specialize in cardio-protective and venotonic tableting (addressing venous insufficiency and capillary fragility). Our purified micronized Purified Flavonoid Fractions (Diosmin/Hesperidin 90:10 ratio) and standardized Rutin NF11 integrate smoothly into solid-dose compounding lines. Micronized down to D90 <5 μm, our powders achieve rapid dissolution and peak bioavailability without excipient clumping during high-speed rotary compression.
2. Marine Cosmeceuticals & Dermal Barrier Creams
The Black Sea cosmetic cluster produces high-end topical skincare formulated to counteract coastal UV exposure and wind-induced oxidative stress. Formulators integrate our Osmanthus Flower Flavonoids, Rosa Roxburghii Extract, and High-Purity Blue Copper Peptide (GHK-Cu) to inhibit matrix metalloproteinases (MMPs), diminish melanin deposition, and speed cellular renewal in anti-aging emulsified serums.
3. Functional Enological Additives & Viticulture Synergies
With the historic Bessarabian and Shabo wine districts positioned in direct proximity to Odesa, functional enology is expanding rapidly. Winemakers and non-alcoholic functional beverage producers utilize our Instant Black Tea Polyphenols and Fruit Anthocyanin Powders (Tart Cherry, Prickly Pear) as natural coloring agents, oxidation protectors, and astringency modulators that eliminate synthetic colorants while preserving clean-label status.
4. Fortified Dietary Supplement Premixes & Instant Drinks
Ukrainian consumers increasingly prioritize preventative wellness, immune resilience, and adaptogenic blends. Local sports nutrition brands and contract packers in Odesa source our water-soluble Cordyceps Polysaccharides, Ginseng Extract Ginsenosides, and Spray-Dried Berry Powders for single-serve sachet stick-packs, effervescent immunity formulations, and functional dry-mix health beverages.
Supply Chain Resilience
Logistics Pathways & Regulatory Conformance for Ukrainian Importers
Global supply chain dynamics have altered traditional maritime trade routes servicing Southern Ukraine. Procuring botanical extracts requires robust logistics contingencies, temperature-controlled multimodal corridors, and unyielding compliance with Ukrainian and European pharmacopeial regulations.
CORRIDOR 01
Constanța / Galați Feeder
Ocean container dispatch from Qingdao/Shanghai to Constanța (Romania) or Danube barge routing (Galați/Izmail/Reni) straight through to Odesa bonded terminals.
CORRIDOR 02
Cross-Border Rail / Truck
Rail-freight transit across the Eurasian corridor arriving into Polish/Slovakian intermodal hubs, transloaded to bonded TIR trucks direct to Odesa customs points.
CORRIDOR 03
Air Express Priority
Direct air courier from Xi'an (XIY) to Warsaw or Chișinău airport, followed by dedicated temperature-regulated road delivery within 5–7 business days for pilot batches.
COMPLIANCE
SPhU & EU Standards
All lots align with the State Pharmacopoeia of Ukraine (ДФУ) and EU Regulation 396/2005 (Pesticide limits), with GC-MS/MS 400+ pesticide screens and ICP-MS heavy metal validation.
To assist customs brokerages in Odesa, Xi'an Sirn Bio-Tech supplies certified Commercial Invoices, Packing Lists with declared Net/Gross tare weights, Phytosanitary Certificates issued by China Customs (GACC), Non-GMO Declarations, TSE/BSE-Free Certificates, and detailed production flowcharts.
Direct Factory Advantage
Xi'an Sirn Bio-Tech: Academic R&D Coupled with Industrial Scale
Headquartered in Xi'an—the cradle of China's Qinba Mountain medicinal botanical reserve—Xi'an Sirn Bio-Tech Co., Ltd. bridges raw agricultural provenance and cutting-edge industrial isolation chemistry. We do not operate as simple repackers or brokers; our clients in Ukraine transact directly with the manufacturing source.
University Joint Laboratories
We maintain joint analytical research operations with Xi'an Jiaotong University, Northwest University, and Xi'an University of Science and Technology. This academic infrastructure enables molecular fingerprinting, polymorph analysis, and custom enzyme catalysis for specific bioflavonoid glycosides.
In-House Analytical Center
Our QC laboratory runs dual Agilent 1260 HPLC units, Shimadzu Gas Chromatography (GC-FID/ECD for pesticide screens), UV-Vis double-beam spectrophotometers, and atomic absorption spectrometers. We analyze every lot for identity, heavy metals (Pb, As, Cd, Hg), and microbial bioburden before dispatch.
Scalable Pilot-to-Bulk Flexibility
With 2 standard production facilities, 4 commercial lines, and 2 pilot lines, we lower procurement barriers. Our 1 kg MOQ permits Ukrainian pharmaceutical formulation teams to execute preliminary benchtop validation and stability testing prior to committing to 25 kg fiber drums or multi-ton contracts.
Procurement Intelligence
Frequently Asked Questions by Odesa Procurement Directors
Direct technical and operational clarifications regarding testing protocols, incoterms, customized blending, and regulatory dossier support for cross-border transactions.
How do you verify bioflavonoid purity and rule out synthetic adulteration? +
We employ gradient reversed-phase High-Performance Liquid Chromatography (RP-HPLC) linked to diode array detectors (DAD), evaluating target retention times against USP/EP certified reference standards. In products frequently prone to adulteration—such as Quercetin or Citrus Hesperidin—we run LC-MS/MS isotopic ratio analysis to confirm plant origin and ensure synthetic additives or unrelated aglycones are not present. Batch HPLC chromatograms are delivered alongside the physical shipment.
What documentation accompanies export shipments bound for Odesa? +
Every export consignment arrives with a batch-specific Certificate of Analysis (COA), formal Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), Flowchart of Manufacturing, Statement of Allergen Absence, Non-GMO Certification, and GACC-issued Official Phytosanitary Certificate. For pharmaceutical buyers compiling registration dossiers, we supply stability testing summaries under Climatic Zone II parameters (25°C / 60% RH).
What is the minimum order quantity (MOQ) for custom-milled or ratio extracts? +
Standard catalog powders and standardized bioflavonoid isolates start at an accessible 1 kg MOQ in sealed multi-layer aluminum barrier foil pouches. For bespoke specifications (e.g., custom mesh sizes such as 200-mesh superfine, custom ratio extraction like 30:1, or carrier-free vacuum freeze-drying), the minimum run begins at 25 kg to 50 kg utilizing our specialized pilot production lines.
How do you handle heavy metal, pesticide, and microbiological limits under Ukrainian regulations? +
Our extracts strictly comply with the State Pharmacopoeia of Ukraine (SPhU) and harmonized EU Pharmacopoeia limits: Lead (Pb) <3.0 ppm (or <1.0 ppm on demand), Cadmium (Cd) <1.0 ppm, Mercury (Hg) <0.1 ppm, and Arsenic (As) <1.0 ppm via Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Pesticide testing screens 400+ compounds, verifying absence of banned organochlorines and organophosphates. Total Aerobic Microbial Count (TAMC) is standardly <1,000 CFU/g with non-detectable E. coli and Salmonella.
What are the lead times and shipping transit options to Odesa given current logistics channels? +
In-stock ingredients are dispatched from our Xi'an export hub within 48 to 72 hours. Priority air courier transit to regional transport hubs (Warsaw or Chișinău) followed by secure cross-border road delivery to Odesa takes approximately 7–10 days. Ocean container loads routed through Constanța or rail freights typically average 30–45 days depending on the selected intermodal routing. Full tracking and customs transit documentation are provided.
Can Xi'an Sirn Bio-Tech produce proprietary OEM/ODM dry blends and premixes? +
Yes. Our GMP workshop is equipped with ribbon blenders, 3D tumble mixers, fluid-bed granulators, and cleanroom packaging suites. We formulate tailored antioxidant blends (e.g., Tart Cherry Anthocyanins + Black Tea Polyphenols + Vitamin C), adjust bulk densities for automated capsule filling machines, and package finished formulations into custom-labeled 25 kg drums or consumer-ready private label sachets.
Request Complete Bioflavonoid Technical Dossiers & Pricing
Connect directly with Xi'an Sirn Bio-Tech's technical export specialists. Receive comprehensive HPLC chromatograms, heavy metal screenings, dynamic pilot-scale pricing, and free pre-shipment evaluation samples tailored for your facility in Odesa.